U4/U6-U5 snRNP complex subunit PRP8 [Saccharomyces cerevisiae S288C]

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PRPF8 defects cause missplicing in myeloid malignancies. [Leukemia. 2015]
PRPF8 defects cause missplicing in myeloid malignancies.
Kurtovic-Kozaric A, Przychodzen B, Singh J, Konarska MM, Clemente MJ, Otrock ZK, Nakashima M, Hsi ED, Yoshida K, Shiraishi Y, et al. Leukemia. 2015 Jan; 29(1):126-36. Epub 2014 Apr 30.
A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. [Nat Struct Mol Biol. 2013]
A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation.
Schellenberg MJ, Wu T, Ritchie DB, Fica S, Staley JP, Atta KA, LaPointe P, MacMillan AM. Nat Struct Mol Biol. 2013 Jun; 20(6):728-34. Epub 2013 May 19.
Structural elucidation of a PRP8 core domain from the heart of the spliceosome. [Nat Struct Mol Biol. 2008]
Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Ritchie DB, Schellenberg MJ, Gesner EM, Raithatha SA, Stuart DT, Macmillan AM. Nat Struct Mol Biol. 2008 Nov; 15(11):1199-205. Epub 2008 Oct 2.

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U4/U6-U5 snRNP complex subunit PRP8 [Saccharomyces cerevisiae S288C]
U4/U6-U5 snRNP complex subunit PRP8 [Saccharomyces cerevisiae S288C]
gi|6321959|ref|NP_012035.1|

Protein
Caenorhabditis elegans transformer protein (tra-1, expressed in L2 stage) mRNA, ...
Caenorhabditis elegans transformer protein (tra-1, expressed in L2 stage) mRNA, complete cds
gi|156471|gb|M94130.1|CELTRA1B

Nucleotide
Metastatic Large Cell Neuroendocrine Carcinoma
Metastatic Large Cell Neuroendocrine Carcinoma

MedGen
Metastatic Bone Sarcoma
Metastatic Bone Sarcoma

MedGen
Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metast...
Unknown Primary Tumor (Except for EBV-Related and HPV-Related Tumors) and Metastatic Cervical Adenopathy by AJCC v8 Stage

MedGen

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Protein