RecName: Full=E3 ubiquitin-protein ligase HUWE1; AltName: Full=ARF-bin - Protein

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The E3 ligase HUWE1 increases the sensitivity of CRC to oxaliplatin through TOMM20 degradation. [Oncogene. 2024]
The E3 ligase HUWE1 increases the sensitivity of CRC to oxaliplatin through TOMM20 degradation.
Lee C, Park SH, Yoon SK. Oncogene. 2024 Feb; 43(9):636-649. Epub 2024 Jan 6.
A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RARα pathway in Chinese individuals. [Andrology. 2024]
A novel SNP in HUWE1 promoter confers increased risk of NOA by affecting the RA/RARα pathway in Chinese individuals.
Shan X, Zhang X, Huang G, Lv J, Ye Z, Jiang C, Jiang X, Cheng J, Lin H, Jiang H, et al. Andrology. 2024 Feb; 12(2):338-348. Epub 2023 Jun 19.
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation. [Elife. 2023]
HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation.
Scinicariello S, Soderholm A, Schäfer M, Shulkina A, Schwartz I, Hacker K, Gogova R, Kalis R, Froussios K, Budroni V, et al. Elife. 2023 Mar 24; 12. Epub 2023 Mar 24.

RefSeq genomic sequence
See the genomic reference sequence for the HUWE1 gene (NG_016261.2).
RefSeq protein isoforms
See 99 reference sequence protein isoforms for the HUWE1 gene.

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Q7Z6Z7 [Domain Mapping of Disease Mut...]
Q7Z6Z7
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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reagents [ExactAntigen/Labome]
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RecName: Full=E3 ubiquitin-protein ligase HUWE1; AltName: Full=ARF-binding prote...
RecName: Full=E3 ubiquitin-protein ligase HUWE1; AltName: Full=ARF-binding protein 1; Short=ARF-BP1; AltName: Full=HECT, UBA and WWE domain-containing protein 1; AltName: Full=HECT-type E3 ubiquitin transferase HUWE1; AltName: Full=Homologous to E6AP carboxyl terminus homologous protein 9; Short=HectH9; AltName: Full=Large structure of UREB1; Short=LASU1; AltName: Full=Mcl-1 ubiquitin ligase E3; Short=Mule; AltName: Full=Upstream regulatory element-binding protein 1; Short=URE-B1; Short=URE-binding protein 1
gi|73915353|sp|Q7Z6Z7.3|HUWE1_HUMAN

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