RecName: Full=Probable G-protein coupled receptor 139; AltName: Full=G - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Highlight Sequence Features
Opens the Highlight Feature Bar and highlights feature annotations from the FEATURES table of the record. The Highlight Feature Bar can be used to navigate to and highlight other features and provides links to display the highlighted region separately. Links in the FEATURES table will also highlight the corresponding region of the sequence. More...
Find in this Sequence
Finds sub-sequences or patterns in the sequence and highlights the matching regions. The tool works with standard single letter nucleotide or protein codes including ambiguities and can match Prosite patterns in protein sequences. More...

Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139. [Eur J Pharmacol. 2023]
Pharmacological characterization of novel small molecule agonists and antagonists for the orphan receptor GPR139.
Pallareti L, Rath TF, Trapkov B, Tsonkov T, Nielsen AT, Harpsøe K, Gentry PR, Bräuner-Osborne H, Gloriam DE, Foster SR. Eur J Pharmacol. 2023 Mar 15; 943:175553. Epub 2023 Feb 2.
Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor. [ACS Med Chem Lett. 2015]
Identification and SAR of Glycine Benzamides as Potent Agonists for the GPR139 Receptor.
Dvorak CA, Coate H, Nepomuceno D, Wennerholm M, Kuei C, Lord B, Woody D, Bonaventure P, Liu C, Lovenberg T, et al. ACS Med Chem Lett. 2015 Sep 10; 6(9):1015-8. Epub 2015 Jul 20.
Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139. [J Chem Inf Model. 2014]
Computer-aided discovery of aromatic l-α-amino acids as agonists of the orphan G protein-coupled receptor GPR139.
Isberg V, Andersen KB, Bisig C, Dietz GP, Bräuner-Osborne H, Gloriam DE. J Chem Inf Model. 2014 Jun 23; 54(6):1553-7. Epub 2014 May 30.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the GPR139 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

RecName: Full=Probable G-protein coupled receptor 139; AltName: Full=G(q)-couple...
RecName: Full=Probable G-protein coupled receptor 139; AltName: Full=G(q)-coupled orphan receptor GPRg1; AltName: Full=G-protein-coupled receptor PGR3
gi|74762300|sp|Q6DWJ6.1|GP139_HUMAN

Protein
Muscular Dystrophies
Muscular Dystrophies
A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET...<br/>Year introduced: 2000(1966)

MeSH
Vitamin D Response Element
Vitamin D Response Element
A DNA sequence that is found in the promoter region of vitamin D regulated genes. Vitamin D receptor (RECEPTOR, CALCITRIOL) binds to and regulates the activity of genes contai...<br/>Year introduced: 2002

MeSH
Clustered Regularly Interspaced Short Palindromic Repeats
Clustered Regularly Interspaced Short Palindromic Repeats
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems....<br/>Year introduced: 2014

MeSH

Your browsing activity is empty.

Activity recording is turned off.

Protein