inosine monophosphate dehydrogenase type II [Homo sapiens]

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Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer. [J Transl Med. 2024]
Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer.
Huang Y, Chan S, Chen S, Liu X, Li M, Zheng L, Dong Z, Yang Z, Liu Z, Zhou D, et al. J Transl Med. 2024 Feb 3; 22(1):133. Epub 2024 Feb 3.
Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. [J Biol Chem. 2023]
Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
O'Neill AG, Burrell AL, Zech M, Elpeleg O, Harel T, Edvardson S, Mor-Shaked H, Rippert AL, Nomakuchi T, Izumi K, et al. J Biol Chem. 2023 Aug; 299(8):105012. Epub 2023 Jul 4.
Genetic analysis of IMPDH2 gene in Taiwanese patients with isolated or combined dystonia. [Parkinsonism Relat Disord. 2023]
Genetic analysis of IMPDH2 gene in Taiwanese patients with isolated or combined dystonia.
Chen PS, Wu MC, Tai CH, Chang YY, Lan MY, Chen YF, Lin HI, Lee NC, Lin CH. Parkinsonism Relat Disord. 2023 Feb; 107:105294. Epub 2023 Jan 17.

RefSeq genomic sequence
See the genomic reference sequence for the IMPDH2 gene (NG_012091.1).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the IMPDH2 gene.

Nucleotide
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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

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Protein