Leucine-zipper-like transcription regulator 1 [Homo sapiens]

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Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome. [Cell Rep. 2024]
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome.
Busley AV, Gutiérrez-Gutiérrez Ó, Hammer E, Koitka F, Mirzaiebadizi A, Steinegger M, Pape C, Böhmer L, Schroeder H, Kleinsorge M, et al. Cell Rep. 2024 Jul 23; 43(7):114448. Epub 2024 Jul 13.
Prenatal diagnosis of autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants presented with thick nuchal translucency and cardiac abnormalities. [Prenat Diagn. 2023]
Prenatal diagnosis of autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants presented with thick nuchal translucency and cardiac abnormalities.
Yu QX, Zhen L, Lin XM, Wen YJ, Li DZ. Prenat Diagn. 2023 Dec; 43(13):1662-1665. Epub 2023 Nov 7.
Exome Survey and Candidate Gene Re-Sequencing Identifies Novel Exstrophy Candidate Genes and Implicates LZTR1 in Disease Formation. [Biomolecules. 2023]
Exome Survey and Candidate Gene Re-Sequencing Identifies Novel Exstrophy Candidate Genes and Implicates LZTR1 in Disease Formation.
Köllges R, Stegmann J, Schneider S, Waffenschmidt L, Fazaal J, Breuer K, Hilger AC, Dworschak GC, Mingardo E, Rösch W, et al. Biomolecules. 2023 Jul 13; 13(7). Epub 2023 Jul 13.

RefSeq genomic sequence
See the genomic reference sequence for the LZTR1 gene (NG_034193.1).
RefSeq protein
See the reference protein sequence for leucine-zipper-like transcriptional regulator 1 (NP_006758.2).

Nucleotide
Nucleotide sequence from coding region
PubMed
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Taxonomy
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Nucleotide NIH cDNA clone
BioSystems
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Gene
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MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Leucine-zipper-like transcription regulator 1 [Homo sapiens]
Leucine-zipper-like transcription regulator 1 [Homo sapiens]
gi|49114072|gb|AAH26214.2|

Protein
67255209-cf26-40fb-85d3-a88052d961cc-dtol
67255209-cf26-40fb-85d3-a88052d961cc-dtol

biosample
OK_RR_rep5
OK_RR_rep5

biosample
Chain B, F-box/LRR-repeat protein 3
Chain B, F-box/LRR-repeat protein 3
gi|460417597|pdb|4I6J|B

Protein

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Protein