phospholipase C, beta 2 variant, partial [Homo sapiens]

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Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals. [Mol Med Rep. 2020]
Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.
Zhang H, Xie T, Shui Y, Qi Y. Mol Med Rep. 2020 Jan; 21(1):420-428. Epub 2019 Nov 6.
Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133(+)/EpCAM(+) phenotype: a promising target for preventing progression of TNBC. [BMC Cancer. 2017]
Up-modulation of PLC-β2 reduces the number and malignancy of triple-negative breast tumor cells with a CD133(+)/EpCAM(+) phenotype: a promising target for preventing progression of TNBC.
Brugnoli F, Grassilli S, Lanuti P, Marchisio M, Al-Qassab Y, Vezzali F, Capitani S, Bertagnolo V. BMC Cancer. 2017 Sep 4; 17(1):617. Epub 2017 Sep 4.
Nuclear factor-κB regulates expression of platelet phospholipase C-β2 (PLCB2). [Thromb Haemost. 2016]
Nuclear factor-κB regulates expression of platelet phospholipase C-β2 (PLCB2).
Mao G, Jin J, Kunapuli SP, Rao AK. Thromb Haemost. 2016 Oct 28; 116(5):931-940. Epub 2016 Jul 28.

RefSeq genomic sequence
See the genomic reference sequence for the PLCB2 gene (NG_052867.1).
RefSeq protein isoforms
See 56 reference sequence protein isoforms for the PLCB2 gene.

Nucleotide
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Chain B, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2
Chain B, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2
gi|119389490|pdb|2FJU|B

Protein
Homologene neighbors for GEO Profiles (Select 56545811) (0)
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Homologene neighbors for GEO Profiles (Select 56539228) (0)
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Homologene neighbors for GEO Profiles (Select 56538595) (0)
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Homologene neighbors for GEO Profiles (Select 56573289) (0)
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Protein