eIF-2B [Homo sapiens]

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Shielding the mRNA-translation factor eIF2B from inhibitory p-eIF2 as a viral strategy to evade protein kinase R-mediated innate immunity. [Curr Opin Immunol. 2022]
Shielding the mRNA-translation factor eIF2B from inhibitory p-eIF2 as a viral strategy to evade protein kinase R-mediated innate immunity.
Wuerth JD, Weber F. Curr Opin Immunol. 2022 Oct; 78:102251. Epub 2022 Oct 12.
De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction. [Diabetes. 2020]
De Novo Mutations in EIF2B1 Affecting eIF2 Signaling Cause Neonatal/Early-Onset Diabetes and Transient Hepatic Dysfunction.
De Franco E, Caswell R, Johnson MB, Wakeling MN, Zung A, Dũng VC, Bích Ngọc CT, Goonetilleke R, Vivanco Jury M, El-Khateeb M, et al. Diabetes. 2020 Mar; 69(3):477-483. Epub 2019 Dec 27.
eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response. [Science. 2019]
eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A. Science. 2019 May 3; 364(6439):491-495.

RefSeq genomic sequence
See the genomic reference sequence for the EIF2B1 gene (NG_015862.2).
RefSeq protein
See the reference protein sequence for translation initiation factor eIF2B subunit alpha (NP_001405.1).

Nucleotide
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BioSystems
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Related structures

MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

602042888F1 NCI_CGAP_Brn67 Homo sapiens cDNA clone IMAGE:4180844 5', mRNA sequen...
602042888F1 NCI_CGAP_Brn67 Homo sapiens cDNA clone IMAGE:4180844 5', mRNA sequence
gi|11615482|gnl|dbEST|6964416|gb|BF 9.1|

Nucleotide

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Protein