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TPA_exp: SF3b10 [Homo sapiens]

GenBank: DAA00073.1

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Protein 3D Structure

The cryo-EM structure of human post-Bact complex

PDB: 8I0V

Source: Homo sapiens

Method: Electron Microscopy

Resolution: 3 Å

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Articles about the SF3B5 gene

Structural basis of branch site recognition by the human spliceosome. [Science. 2022]
Structural basis of branch site recognition by the human spliceosome.
Tholen J, Razew M, Weis F, Galej WP. Science. 2022 Jan 7; 375(6576):50-57. Epub 2021 Nov 25.
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex. [Nat Commun. 2017]
Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A-SF3b complex.
Teng T, Tsai JH, Puyang X, Seiler M, Peng S, Prajapati S, Aird D, Buonamici S, Caleb B, Chan B, et al. Nat Commun. 2017 May 25; 8:15522. Epub 2017 May 25.
Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations. [Mol Cell. 2016]
Molecular Architecture of SF3b and Structural Consequences of Its Cancer-Related Mutations.
Cretu C, Schmitzová J, Ponce-Salvatierra A, Dybkov O, De Laurentiis EI, Sharma K, Will CL, Urlaub H, Lührmann R, Pena V. Mol Cell. 2016 Oct 20; 64(2):307-319. Epub 2016 Oct 6.

Reference sequence information

RefSeq protein
See the reference protein sequence for splicing factor 3B subunit 5 (NP_112577.1).

More about the SF3B5 gene

Enables RNA binding activity and splicing factor binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleoplasm. Part ...
Also Known As: SF3b10, Ysf3

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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

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