3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble), isoform CR - Protein

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Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1. [J Biol Chem. 2022]
Antidiabetic drug metformin suppresses tumorigenesis through inhibition of mevalonate pathway enzyme HMGCS1.
Chen Y, Li M, Yang Y, Lu Y, Li X. J Biol Chem. 2022 Dec; 298(12):102678. Epub 2022 Nov 8.
Compartmentalized activities of HMGCS1 control cervical cancer radiosensitivity. [Cell Signal. 2023]
Compartmentalized activities of HMGCS1 control cervical cancer radiosensitivity.
Zhang X, Sun C, Wan J, Zhang X, Jia Y, Zhou C. Cell Signal. 2023 Jan; 101:110507. Epub 2022 Oct 31.
Pan-cancer analysis reveals the oncogenic role of 3-hydroxy-3-methylglutaryl-CoA synthase 1. [Cancer Rep (Hoboken). 2022]
Pan-cancer analysis reveals the oncogenic role of 3-hydroxy-3-methylglutaryl-CoA synthase 1.
Zhou C, Wang Z, Cao Y, Zhao L. Cancer Rep (Hoboken). 2022 Sep; 5(9):e1562. Epub 2021 Sep 22.

RefSeq protein isoforms
See 11 reference sequence protein isoforms for the HMGCS1 gene.

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Nucleotide
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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) [Homo sapiens]
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) [Homo sapiens]
gi|30583443|gb|AAP35966.1|

Protein
Pilosella arnoseroides (1284)
Nucleotide
PREDICTED: uncharacterized protein LOC103492117 [Cucumis melo]
PREDICTED: uncharacterized protein LOC103492117 [Cucumis melo]
gi|659099339|ref|XP_008450550.1|

Protein
TSA: Armillaria ostoyae RNA1 s_2_sequencecontig182 transcribed RNA sequence
TSA: Armillaria ostoyae RNA1 s_2_sequencecontig182 transcribed RNA sequence
gi|480500338|gb|GAHM01000095.1||gnl GAHM01|s_2_sequencecontig182

Nucleotide
TSA: Armillaria ostoyae RNA1 s_2_sequencecontig23 transcribed RNA sequence
TSA: Armillaria ostoyae RNA1 s_2_sequencecontig23 transcribed RNA sequence
gi|480500419|gb|GAHM01000014.1||gnl GAHM01|s_2_sequencecontig23

Nucleotide

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Protein