chloride intracellular channel 2, isoform CRA_a [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Tilapia and human CLIC2 structures are highly conserved. [Biochem Biophys Res Commun. 2018]
Tilapia and human CLIC2 structures are highly conserved.
Zeng J, Li Z, Lui EY, Lam SH, Swaminathan K. Biochem Biophys Res Commun. 2018 Jan 8; 495(2):1752-1757. Epub 2017 Dec 2.
An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity. [Hum Mol Genet. 2012]
An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity.
Takano K, Liu D, Tarpey P, Gallant E, Lam A, Witham S, Alexov E, Chaubey A, Stevenson RE, Schwartz CE, et al. Hum Mol Genet. 2012 Oct 15; 21(20):4497-507. Epub 2012 Jul 19.
A missense mutation in CLIC2 associated with intellectual disability is predicted by in silico modeling to affect protein stability and dynamics. [Proteins. 2011]
A missense mutation in CLIC2 associated with intellectual disability is predicted by in silico modeling to affect protein stability and dynamics.
Witham S, Takano K, Schwartz C, Alexov E. Proteins. 2011 Aug; 79(8):2444-54. Epub 2011 May 31.

RefSeq genomic sequence
See the genomic reference sequence for the CLIC2 gene (NG_012497.2).
RefSeq protein
See the reference protein sequence for chloride intracellular channel protein 2 (NP_001280.3).

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Bacillus subtilis strain QYCK 26 contig00002, whole genome shotgun sequence
Bacillus subtilis strain QYCK 26 contig00002, whole genome shotgun sequence
gi|2247476600|ref|NZ_JAKKEO01000000 gnl|WGS:NZ_JAKKEO01|contig00002

Nucleotide
UI-R-BU0-ani-e-06-0-UI.s1 UI-R-BU0 Rattus norvegicus cDNA clone UI-R-BU0-ani-e-0...
UI-R-BU0-ani-e-06-0-UI.s1 UI-R-BU0 Rattus norvegicus cDNA clone UI-R-BU0-ani-e-06-0-UI 3', mRNA sequence
gi|7175904|gnl|dbEST|3952283|gb|AW5 .1|

Nucleotide
Mre11 MRE11 homolog, double strand break repair nuclease [Rattus norvegicus]
Mre11 MRE11 homolog, double strand break repair nuclease [Rattus norvegicus]
Gene ID:64046

Gene

Your browsing activity is empty.

Activity recording is turned off.

Protein