hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix tran - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Understanding Hypoxia-Driven Tumorigenesis: The Interplay of HIF1A, DNA Methylation, and Prolyl Hydroxylases in Head and Neck Squamous Cell Carcinoma. [Int J Mol Sci. 2024]
Understanding Hypoxia-Driven Tumorigenesis: The Interplay of HIF1A, DNA Methylation, and Prolyl Hydroxylases in Head and Neck Squamous Cell Carcinoma.
Ostapowicz J, Ostrowska K, Rawłuszko-Wieczorek AA, Wojtera B, Koczot S, Golusiński W, Suchorska WM. Int J Mol Sci. 2024 Jun 12; 25(12). Epub 2024 Jun 12.
Activation of the hypoxia-inducible factor pathway protects against acute ischemic stroke by reprogramming central carbon metabolism. [Theranostics. 2024]
Activation of the hypoxia-inducible factor pathway protects against acute ischemic stroke by reprogramming central carbon metabolism.
Madai S, Kilic P, Schmidt RM, Bas-Orth C, Korff T, Büttner M, Klinke G, Poschet G, Marti HH, Kunze R. Theranostics. 2024; 14(7):2856-2880. Epub 2024 Apr 29.
Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis. [J Neuroinflammation. 2024]
Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis.
Altınönder İ, Kaya M, Yentür SP, Çakar A, Durmuş H, Yegen G, Özkan B, Parman Y, Sawalha AH, Saruhan-Direskeneli G. J Neuroinflammation. 2024 May 11; 21(1):126. Epub 2024 May 11.

RefSeq genomic sequence
See the genomic reference sequence for the HIF1A gene (NG_029606.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the HIF1A gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Profile neighbors for GEO Profiles (Select 38460817) (199)
GEO Profiles
Profile neighbors for GEO Profiles (Select 38470126) (199)
GEO Profiles
Profile neighbors for GEO Profiles (Select 38485094) (199)
GEO Profiles
BioAssays, RNAi Target, Active for Gene (Select 98682) (1)
PubChem BioAssay
Concise Conserved Domain Links for Protein (Select 1955849477) (1)
Conserved Domains

Your browsing activity is empty.

Activity recording is turned off.

Protein