integrin alpha-4 isoform 1 preproprotein [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals. [Eur J Haematol. 2022]
Low CD49d expression in newly diagnosed chronic lymphocytic leukaemia may be associated with high-risk features and reduced treatment-free-intervals.
Elizabeth S, Aidan K, David OB, Deirdre W, Sarah B, Emer A, Kanthi P, Crotty GM, Aileen W, Michelle C, et al. Eur J Haematol. 2022 Nov; 109(5):441-446. Epub 2022 Aug 9.
Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis. [Cancer Lett. 2020]
Integrin α4 up-regulation activates the hedgehog pathway to promote arsenic and benzo[α]pyrene co-exposure-induced cancer stem cell-like property and tumorigenesis.
Xie J, Yang P, Lin HP, Li Y, Clementino M, Fenske W, Yang C, Wang C, Wang Z. Cancer Lett. 2020 Nov 28; 493:143-155. Epub 2020 Aug 26.
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression. [Blood. 2020]
CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression.
Tissino E, Pozzo F, Benedetti D, Caldana C, Bittolo T, Rossi FM, Bomben R, Nanni P, Chivilò H, Cattarossi I, et al. Blood. 2020 Apr 9; 135(15):1244-1254.

RefSeq genomic sequence
See the genomic reference sequence for the ITGA4 gene (NG_050623.2).
RefSeq mRNA
See reference mRNA sequence for the ITGA4 gene (NM_000885.6).
RefSeq protein isoforms
See the other reference sequence protein isoform for the ITGA4 gene (NP_001303241.1).

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (List)
PubChem BioAssays done on the protein target
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_000876 [Domain Mapping of Disease Mut...]
NP_000876
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor) protein [Guide to Pharmacology]
integrin, alpha 4 subunit (antigen CD49D, alpha 4 subunit of VLA-4 receptor) protein
Guide to Pharmacology
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

Your browsing activity is empty.

Activity recording is turned off.

Protein