HLA class II histocompatibility antigen gamma chain isoform c [Homo sa - Protein

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CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors. [Cancer Immunol Immunother. 2024]
CD74 is associated with inflamed tumor immune microenvironment and predicts responsiveness to PD-1/CTLA-4 bispecific antibody in patients with solid tumors.
Wang J, Li X, Xiao G, Desai J, Frentzas S, Wang ZM, Xia Y, Li B. Cancer Immunol Immunother. 2024 Jan 27; 73(2):36. Epub 2024 Jan 27.
Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients. [Front Immunol. 2023]
Macrophage migration inhibitory factor receptor CD74 expression is associated with expansion and differentiation of effector T cells in COVID-19 patients.
Westmeier J, Brochtrup A, Paniskaki K, Karakoese Z, Werner T, Sutter K, Dolff S, Limmer A, Mittermüller D, Liu J, et al. Front Immunol. 2023; 14:1236374. Epub 2023 Oct 25.
Increased Expression of CD74 in Atherosclerosis Associated with Inflammatory Responses of Endothelial Cells and Macrophages. [Biochem Genet. 2024]
Increased Expression of CD74 in Atherosclerosis Associated with Inflammatory Responses of Endothelial Cells and Macrophages.
Ke K, Wu Z, Lin J, Lin L, Huang N, Yang W. Biochem Genet. 2024 Feb; 62(1):294-310. Epub 2023 Jun 19.

RefSeq genomic sequence
See the genomic reference sequence for the CD74 gene (NG_029730.1).
RefSeq mRNA
See reference mRNA sequence for the CD74 gene (NM_001025158.3).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the CD74 gene.

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NP_001020329 [Domain Mapping of Disease Mut...]
NP_001020329
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

Gene Links for GEO Profiles (Select 88399105) (2)
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Homologene neighbors for GEO Profiles (Select 120274363) (0)
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Profile neighbors for GEO Profiles (Select 120275342) (199)
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Profile neighbors for GEO Profiles (Select 120287473) (199)
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Profile neighbors for GEO Profiles (Select 88403265) (48)
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Protein