actin-related protein 2/3 complex subunit 4 [Bos taurus]

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A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay. [HGG Adv. 2022]
A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay.
Laboy Cintron D, Muir AM, Scott A, McDonald M, Monaghan KG, Santiago-Sim T, Wentzensen IM, De Luca C, Italian Undiagnosed Diseases Network, Brancati F, et al. HGG Adv. 2022 Jan 13; 3(1):100072. Epub 2021 Nov 25.
ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis. [J Cell Biochem. 2020]
ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis.
Xu N, Qu GY, Wu YP, Lin YZ, Chen DN, Li XD, Chen SH, Huang JB, Zheng QS, Xue XY, et al. J Cell Biochem. 2020 Jan; 121(1):231-243. Epub 2019 Jun 12.
Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages. [PLoS One. 2013]
Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages.
Ghosh A, Tousif S, Bhattacharya D, Samuchiwal SK, Bhalla K, Tharad M, Kumar S, Prakash P, Kumar P, Das G, et al. PLoS One. 2013; 8(7):e69949. Epub 2013 Jul 22.

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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 1, mRNA (cDNA ...
Homo sapiens apoptosis-inducing factor, mitochondrion-associated, 1, mRNA (cDNA clone MGC:141887 IMAGE:40085139), complete cds
gi|141797017|gb|BC139738.1|

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