charged multivesicular body protein 3 isoform 3 [Homo sapiens]

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CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis. [Int J Oncol. 2024]
CHMP3 promotes the progression of hepatocellular carcinoma by inhibiting caspase‑1‑dependent pyroptosis.
Zheng Y, Yang S, Dai W, Wang J, Bi S, Zhang X, Zheng Z, Sun Y, Wu S, Kong J. Int J Oncol. 2024 Jan; 64(1). Epub 2023 Dec 1.
A homozygous variant in CHMP3 is associated with complex hereditary spastic paraplegia. [J Med Genet. 2023]
A homozygous variant in CHMP3 is associated with complex hereditary spastic paraplegia.
Cohen-Barak E, Danial-Farran N, Chervinsky E, Alimi-Kasem O, Zagairy F, Livneh I, Mawassi B, Hreish M, Khayat M, Lossos A, et al. J Med Genet. 2023 Mar; 60(3):233-240. Epub 2022 Jun 16.
RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis. [Cell. 2021]
RetroCHMP3 blocks budding of enveloped viruses without blocking cytokinesis.
Rheinemann L, Downhour DM, Bredbenner K, Mercenne G, Davenport KA, Schmitt PT, Necessary CR, McCullough J, Schmitt AP, Simon SM, et al. Cell. 2021 Oct 14; 184(21):5419-5431.e16. Epub 2021 Sep 30.

RefSeq mRNA
See reference mRNA sequence for the CHMP3 gene (NM_001193517.2).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the CHMP3 gene.

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NP_001180446 [Domain Mapping of Disease Mut...]
NP_001180446
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

PREDICTED: Homo sapiens TXK tyrosine kinase (TXK), transcript variant X4, mRNA
PREDICTED: Homo sapiens TXK tyrosine kinase (TXK), transcript variant X4, mRNA
gi|2462598760|ref|XM_054350776.1|

Nucleotide
EXC43_RS01385 [Mycoplasmoides pneumoniae]
EXC43_RS01385 [Mycoplasmoides pneumoniae]
Gene ID:66608887

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Protein