pyruvate dehydrogenase kinase, isozyme 2 isoform 2 [Homo sapiens]

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PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma. [Cancer Sci. 2021]
PDK2 leads to cisplatin resistance through suppression of mitochondrial function in ovarian clear cell carcinoma.
Kitamura S, Yamaguchi K, Murakami R, Furutake Y, Higasa K, Abiko K, Hamanishi J, Baba T, Matsumura N, Mandai M. Cancer Sci. 2021 Nov; 112(11):4627-4640. Epub 2021 Sep 13.
PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3. [J Drug Target. 2019]
PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3.
Hu T, Yu S, Li Y, Ren H, Ning Q, Wang J, Liang X, Li M. J Drug Target. 2019 Apr; 27(4):460-465. Epub 2018 Dec 4.
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer. [Cancer Lett. 2016]
Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
Roh JL, Park JY, Kim EH, Jang HJ, Kwon M. Cancer Lett. 2016 Feb 1; 371(1):20-9. Epub 2015 Nov 23.

RefSeq mRNA
See reference mRNA sequence for the PDK2 gene (NM_001199898.2).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the PDK2 gene.

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Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
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reagent reviews [ExactAntigen/Labome]
reagent reviews
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