nucleolar protein 3 isoform C [Homo sapiens]

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Protein 3D Structure

Crystal Structure of apoptosis repressor with CARD (ARC)

PDB: 4UZ0

Source: Homo sapiens

Method: X-ray Diffraction

Resolution: 2.399 Å

Articles about the NOL3 gene

Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin. [Cell Commun Signal. 2021]
Expression of apoptosis repressor with caspase recruitment domain (ARC) in familial adenomatous polyposis (FAP) adenomas and its correlation with DNA mismatch repair proteins, p53, Bcl-2, COX-2 and beta-catenin.
Roser C, Tóth C, Renner M, Herpel E, Schirmacher P. Cell Commun Signal. 2021 Feb 12; 19(1):15. Epub 2021 Feb 12.
The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling. [Cell Commun Signal. 2017]
The role of apoptosis repressor with a CARD domain (ARC) in the therapeutic resistance of renal cell carcinoma (RCC): the crucial role of ARC in the inhibition of extrinsic and intrinsic apoptotic signalling.
Toth C, Funke S, Nitsche V, Liverts A, Zlachevska V, Gasis M, Wiek C, Hanenberg H, Mahotka C, Schirmacher P, et al. Cell Commun Signal. 2017 May 2; 15(1):16. Epub 2017 May 2.
Expression of the apoptosis repressor with caspase recruitment domain (ARC) in liver metastasis of colorectal cancer and its correlation with DNA mismatch repair proteins and p53. [J Cancer Res Clin Oncol. 2016]
Expression of the apoptosis repressor with caspase recruitment domain (ARC) in liver metastasis of colorectal cancer and its correlation with DNA mismatch repair proteins and p53.
Tóth C, Meinrath J, Herpel E, Derix J, Fries J, Buettner R, Schirmacher P, Heikaus S. J Cancer Res Clin Oncol. 2016 May; 142(5):927-35. Epub 2015 Dec 31.

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Reference sequence information

RefSeq genomic sequence
See the genomic reference sequence for the NOL3 gene (NG_029566.1).
RefSeq mRNA
See reference mRNA sequence for the NOL3 gene (NM_001394975.1).
RefSeq protein isoforms
See 19 reference sequence protein isoforms for the NOL3 gene.

More about the NOL3 gene

This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor pro...
Also Known As: ARC, FCM, MYOCL1, MYP, ...

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