dual specificity mitogen-activated protein kinase kinase 1 isoform 1 [ - Protein

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Activating mutations drive human MEK1 kinase using a gear-shifting mechanism. [Biochem J. 2023]
Activating mutations drive human MEK1 kinase using a gear-shifting mechanism.
Patil K, Wang Y, Chen Z, Suresh K, Radhakrishnan R. Biochem J. 2023 Nov 15; 480(21):1733-1751.
Response to MEK Inhibitor Therapy in MAP2K1 (MEK1) K57N Non-Small-Cell Lung Cancer and Genomic Landscape of MAP2K1 Mutations in Non-Small-Cell Lung Cancer. [JCO Precis Oncol. 2022]
Response to MEK Inhibitor Therapy in MAP2K1 (MEK1) K57N Non-Small-Cell Lung Cancer and Genomic Landscape of MAP2K1 Mutations in Non-Small-Cell Lung Cancer.
Cheng ML, Lee JK, Kumar R, Klein H, Raskina K, Schrock AB, Michael KS, Mazor T, Cerami E, Oxnard GR, et al. JCO Precis Oncol. 2022 Nov; 6:e2200382.
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer. [Mol Cancer Ther. 2023]
High-Throughput Functional Evaluation of MAP2K1 Variants in Cancer.
Mizuno S, Ikegami M, Koyama T, Sunami K, Ogata D, Kage H, Yanagaki M, Ikeuchi H, Ueno T, Tanikawa M, et al. Mol Cancer Ther. 2023 Feb 1; 22(2):227-239.

RefSeq genomic sequence
See the genomic reference sequence for the MAP2K1 gene (NG_008305.1).
RefSeq mRNA
See reference mRNA sequence for the MAP2K1 gene (NM_002755.4).
RefSeq protein isoforms
See 6 reference sequence protein isoforms for the MAP2K1 gene.

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NP_002746 [Domain Mapping of Disease Mut...]
NP_002746
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
mitogen-activated protein kinase kinase 1 protein [Guide to Pharmacology]
mitogen-activated protein kinase kinase 1 protein
Guide to Pharmacology
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

scavenger receptor class A member 3 isoform 1 [Homo sapiens]
scavenger receptor class A member 3 isoform 1 [Homo sapiens]
gi|33598924|ref|NP_057324.2|

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