Cataract-causing mutations S78F and S78P of γD-crystallin decrease protein conformational stability and drive aggregation.
Lin N, Zhang Y, Song X, Xu J, Luo C, Tian Q, Yao K, Wu W, Chen X, Hu L. Int J Biol Macromol. 2023 Dec 31; 253(Pt 4):126910. Epub 2023 Sep 21.