bcl-2-binding component 3 isoform 4 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL-2/BCL-XL pathway augmenting apoptosis in ovarian cancer. [Biochim Biophys Acta Mol Basis...]
PUMA overexpression dissociates thioredoxin from ASK1 to activate the JNK/BCL-2/BCL-XL pathway augmenting apoptosis in ovarian cancer.
Chen Y, Li N, Yang J, Li K, Tang M, Zhao X, Guo W, Tong A, Nie C, Peng Y, et al. Biochim Biophys Acta Mol Basis Dis. 2022 Dec 1; 1868(12):166553. Epub 2022 Sep 17.
Expression of p53 up-regulated modulator of apoptosis (PUMA) in non-melanoma skin cancer of long-term immunosuppressed solid organ transplant recipients compared to immunocompetent patients. [Eur J Dermatol. 2021]
Expression of p53 up-regulated modulator of apoptosis (PUMA) in non-melanoma skin cancer of long-term immunosuppressed solid organ transplant recipients compared to immunocompetent patients.
Neuberger A, Menzer C, Volk N, Enk AH, Hadaschik EN, Lonsdorf AS. Eur J Dermatol. 2021 Oct 1; 31(5):609-615.
Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling. [Int J Biol Sci. 2021]
Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling.
Xie S, Zhao C, Chen W, Li G, Xiong Z, Tang X, Zhang F, Xiao H. Int J Biol Sci. 2021; 17(9):2367-2379. Epub 2021 Jun 11.

RefSeq genomic sequence
See the genomic reference sequence for the BBC3 gene (NG_031991.2).
RefSeq mRNA
See reference mRNA sequence for the BBC3 gene (NM_014417.5).
RefSeq protein isoforms
See 10 reference sequence protein isoforms for the BBC3 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CCDS
Link to Consensus CDS
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
HomoloGene
Related HomoloGene
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures
SNP
Related SNPs

NP_055232 [Domain Mapping of Disease Mut...]
NP_055232
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Find Quality Antibodies [GeneTex Inc]
Find Quality Antibodies
GeneTex Inc

Your browsing activity is empty.

Activity recording is turned off.

Protein