SMC5-SMC6 complex localization factor protein 2 isoform 1 [Homo sapien - Protein

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Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response. [EMBO Mol Med. 2023]
Actionable loss of SLF2 drives B-cell lymphomagenesis and impairs the DNA damage response.
Zhang L, Wirth M, Patra U, Stroh J, Isaakidis K, Rieger L, Kossatz S, Milanovic M, Zang C, Demel U, et al. EMBO Mol Med. 2023 Sep 11; 15(9):e16431. Epub 2023 Jul 24.
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy. [Nat Commun. 2022]
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy.
Grange LJ, Reynolds JJ, Ullah F, Isidor B, Shearer RF, Latypova X, Baxley RM, Oliver AW, Ganesh A, Cooke SL, et al. Nat Commun. 2022 Nov 4; 13(1):6664. Epub 2022 Nov 4.
cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia. [Gene. 2002]
cDNA cloning, expression profile and genomic structure of a novel human transcript on chromosome 10q24, and its analyses as a candidate gene for infantile onset spinocerebellar ataxia.
Nikali K, Saharinen J, Peltonen L. Gene. 2002 Oct 16; 299(1-2):111-5.

RefSeq mRNA
See reference mRNA sequence for the SLF2 gene (NM_018121.4).
RefSeq protein isoforms
See 13 reference sequence protein isoforms for the SLF2 gene.

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NP_060591 [Domain Mapping of Disease Mut...]
NP_060591
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome