fatty acyl-CoA reductase 1 [Homo sapiens]

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An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids. [Genet Med. 2021]
An autosomal dominant neurological disorder caused by de novo variants in FAR1 resulting in uncontrolled synthesis of ether lipids.
Ferdinandusse S, McWalter K, Te Brinke H, IJlst L, Mooijer PM, Ruiter JPN, van Lint AEM, Pras-Raves M, Wever E, Millan F, et al. Genet Med. 2021 Apr; 23(4):740-750. Epub 2020 Nov 26.
A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency. [Am J Hum Genet. 2014]
A peroxisomal disorder of severe intellectual disability, epilepsy, and cataracts due to fatty acyl-CoA reductase 1 deficiency.
Buchert R, Tawamie H, Smith C, Uebe S, Innes AM, Al Hallak B, Ekici AB, Sticht H, Schwarze B, Lamont RE, et al. Am J Hum Genet. 2014 Nov 6; 95(5):602-10. Epub 2014 Oct 30.
Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis. [J Biol Chem. 2010]
Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesis.
Honsho M, Asaoku S, Fujiki Y. J Biol Chem. 2010 Mar 19; 285(12):8537-42. Epub 2010 Jan 13.

RefSeq genomic sequence
See the genomic reference sequence for the FAR1 gene (NG_041826.1).
RefSeq mRNA
See reference mRNA sequence for the FAR1 gene (NM_032228.6).
RefSeq protein isoforms
See 5 reference sequence protein isoforms for the FAR1 gene.

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NP_115604 [Domain Mapping of Disease Mut...]
NP_115604
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
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reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

CUE domain-containing protein 2 isoform X5 [Rattus norvegicus]
CUE domain-containing protein 2 isoform X5 [Rattus norvegicus]
gi|2678865582|ref|XP_063143318.1|

Protein
PREDICTED: Rattus norvegicus CUE domain containing 2 (Cuedc2), transcript varian...
PREDICTED: Rattus norvegicus CUE domain containing 2 (Cuedc2), transcript variant X10, mRNA
gi|2678865587|ref|XM_006231466.4|

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