protein dispatched homolog 1 isoform 1 [Homo sapiens]

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DISP1 deficiency: Monoallelic and biallelic variants cause a spectrum of midline craniofacial malformations. [Genet Med. 2024]
DISP1 deficiency: Monoallelic and biallelic variants cause a spectrum of midline craniofacial malformations.
Lavillaureix A, Rollier P, Kim A, Panasenkava V, De Tayrac M, Carré W, Guyodo H, Faoucher M, Poirel E, Akloul L, et al. Genet Med. 2024 Jul; 26(7):101126. Epub 2024 Mar 24.
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane. [J Cell Sci. 2022]
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane.
Ehring K, Manikowski D, Goretzko J, Froese J, Gude F, Jakobs P, Rescher U, Kirchhefer U, Grobe K. J Cell Sci. 2022 Mar 1; 135(5). Epub 2021 Aug 19.
Structure of human Dispatched-1 provides insights into Hedgehog ligand biogenesis. [Life Sci Alliance. 2020]
Structure of human Dispatched-1 provides insights into Hedgehog ligand biogenesis.
Chen H, Liu Y, Li X. Life Sci Alliance. 2020 Aug; 3(8). Epub 2020 Jul 9.

RefSeq genomic sequence
See the genomic reference sequence for the DISP1 gene (NG_009243.2).
RefSeq mRNA
See reference mRNA sequence for the DISP1 gene (NM_032890.5).

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Protein (UniProtKB)
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SNP
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NP_116279 [Domain Mapping of Disease Mut...]
NP_116279
Domain Mapping of Disease Mutations
Ensembl [Ensembl]
Ensembl
GlyGen glycoinformatics resource [GlyGen glycoinformatics resou...]
GlyGen glycoinformatics resource
OncoMX cancer biomarker resource [OncoMX cancer biomarker resou...]
OncoMX cancer biomarker resource
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

UI-CF-DU1-adl-m-01-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA clone UI-CF-DU1-adl-m-01-...
UI-CF-DU1-adl-m-01-0-UI.s1 UI-CF-DU1 Homo sapiens cDNA clone UI-CF-DU1-adl-m-01-0-UI 3', mRNA sequence
gi|19599135|gnl|dbEST|11797364|gb|B 66.1|

Nucleotide
solute carrier family 12 member 6 [Rattus norvegicus]
solute carrier family 12 member 6 [Rattus norvegicus]
gi|157820121|ref|NP_001103100.1|

Protein
transmembrane and ubiquitin-like domain-containing protein 1 isoform X1 [Rattus ...
transmembrane and ubiquitin-like domain-containing protein 1 isoform X1 [Rattus norvegicus]
gi|564345381|ref|XP_006236007.1|

Protein

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Protein