RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha - Protein

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IKKα kinase silencing increases doxorubicin-induced apoptosis through regulation of oxidative DNA damage response in colon cancer cells. [Chem Biol Drug Des. 2023]
IKKα kinase silencing increases doxorubicin-induced apoptosis through regulation of oxidative DNA damage response in colon cancer cells.
Gao J, Zhu L. Chem Biol Drug Des. 2023 May; 101(5):1089-1095. Epub 2022 Dec 27.
Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer. [Br J Cancer. 2022]
Spatial expression of IKK-alpha is associated with a differential mutational landscape and survival in primary colorectal cancer.
Patel M, Pennel KAF, Quinn JA, Hood H, Chang DK, Biankin AV, Rebus S, Roseweir AK, Park JH, Horgan PG, et al. Br J Cancer. 2022 Jun; 126(12):1704-1714. Epub 2022 Feb 16.
IKKα plays a major role in canonical NF-κB signalling in colorectal cells. [Biochem J. 2022]
IKKα plays a major role in canonical NF-κB signalling in colorectal cells.
Prescott JA, Balmanno K, Mitchell JP, Okkenhaug H, Cook SJ. Biochem J. 2022 Feb 11; 479(3):305-325.

RefSeq genomic sequence
See the genomic reference sequence for the CHUK gene (NG_028023.2).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the CHUK gene.

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O15111 [Domain Mapping of Disease Mut...]
O15111
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome

RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-...
RecName: Full=Inhibitor of nuclear factor kappa-B kinase subunit alpha; Short=I-kappa-B kinase alpha; Short=IKK-A; Short=IKK-alpha; Short=IkBKA; Short=IkappaB kinase; AltName: Full=Conserved helix-loop-helix ubiquitous kinase; AltName: Full=I-kappa-B kinase 1; Short=IKK-1; Short=IKK1; AltName: Full=Nuclear factor NF-kappa-B inhibitor kinase alpha; Short=NFKBIKA; AltName: Full=Transcription factor 16; Short=TCF-16
gi|317373368|sp|O15111.2|IKKA_HUMAN

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