RecName: Full=11-beta-hydroxysteroid dehydrogenase 1; Short=11-DH; Sho - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients. [Aging Clin Exp Res. 2023]
11-beta-hydroxysteroid dehydrogenase type 1 (HSD11B1) gene expression in muscle is linked to reduced skeletal muscle index in sarcopenic patients.
Schluessel S, Zhang W, Nowotny H, Bidlingmaier M, Hintze S, Kunz S, Martini S, Mehaffey S, Meinke P, Neuerburg C, et al. Aging Clin Exp Res. 2023 Dec; 35(12):3073-3083. Epub 2023 Nov 9.
Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH. [Cell Death Dis. 2022]
Inhibition of 11β-hydroxysteroid dehydrogenase 1 relieves fibrosis through depolarizing of hepatic stellate cell in NASH.
Lee SY, Kim S, Choi I, Song Y, Kim N, Ryu HC, Lim JW, Kang HJ, Kim J, Seo HR. Cell Death Dis. 2022 Nov 29; 13(11):1011. Epub 2022 Nov 29.
Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry. [Bioengineered. 2021]
Microenvironment-associated gene HSD11B1 may serve as a prognostic biomarker in clear cell renal cell carcinoma: a study based on TCGA, RT‑qPCR, Western blotting, and immunohistochemistry.
Han D, Yu Z, Zhang H, Liu H, Wang B, Qian D. Bioengineered. 2021 Dec; 12(2):10891-10904.

RefSeq genomic sequence
See the genomic reference sequence for the HSD11B1 gene (NG_012081.1).
RefSeq protein isoforms
See 3 reference sequence protein isoforms for the HSD11B1 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

P28845 [Domain Mapping of Disease Mut...]
P28845
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site