RecName: Full=GTP cyclohydrolase 1; AltName: Full=GTP cyclohydrolase I - Protein

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GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner. [Cancer Res. 2023]
GTP Cyclohydrolase Drives Breast Cancer Development and Promotes EMT in an Enzyme-Independent Manner.
Wang Z, Zhang N, Zhang M, Jiang Y, Ng AS, Bridges E, Zhang W, Zeng X, Luo Q, Liang J, et al. Cancer Res. 2023 Oct 13; 83(20):3400-3413.
GTP Cyclohydrolase I as a Potential Drug Target: New Insights into Its Allosteric Modulation via Normal Mode Analysis. [J Chem Inf Model. 2021]
GTP Cyclohydrolase I as a Potential Drug Target: New Insights into Its Allosteric Modulation via Normal Mode Analysis.
Khairallah A, Ross CJ, Tastan Bishop Ö. J Chem Inf Model. 2021 Sep 27; 61(9):4701-4719. Epub 2021 Aug 27.
Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis. [Free Radic Biol Med. 2021]
Epigenetic silencing of GCH1promotes hepatocellular carcinoma growth by activating superoxide anion-mediated ASK1/p38 signaling via inhibiting tetrahydrobiopterin de novo biosynthesis.
Zhong GC, Zhao ZB, Cheng Y, Wang YB, Qiu C, Mao LH, Hu JJ, Cai D, Liu Y, Gong JP, et al. Free Radic Biol Med. 2021 May 20; 168:81-94. Epub 2021 Mar 26.

RefSeq genomic sequence
See the genomic reference sequence for the GCH1 gene (NG_008647.2).
RefSeq protein isoforms
See 8 reference sequence protein isoforms for the GCH1 gene.

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P30793 [Domain Mapping of Disease Mut...]
P30793
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Ful...
RecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Full=Hemoglobin alpha chain
gi|110831920|sp|P84216.2|HBA_BATEA

Protein
PREDICTED: Danio rerio mitogen-activated protein kinase kinase kinase kinase 3b ...
PREDICTED: Danio rerio mitogen-activated protein kinase kinase kinase kinase 3b (map4k3b), transcript variant X3, mRNA
gi|2800604090|ref|XM_021473172.2|

Nucleotide
interleukin-15 isoform X1 [Mus musculus]
interleukin-15 isoform X1 [Mus musculus]
gi|568956208|ref|XP_006530772.1|

Protein
PREDICTED: Mus musculus interleukin 15 (Il15), transcript variant X3, mRNA
PREDICTED: Mus musculus interleukin 15 (Il15), transcript variant X3, mRNA
gi|1907187388|ref|XM_006530706.5|

Nucleotide
PREDICTED: Mus musculus interleukin 15 (Il15), transcript variant X16, mRNA
PREDICTED: Mus musculus interleukin 15 (Il15), transcript variant X16, mRNA
gi|1907187415|ref|XM_030243304.2|

Nucleotide

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Protein