RecName: Full=Actin-related protein 2/3 complex subunit 4; AltName: Fu - Protein

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A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay. [HGG Adv. 2022]
A recurrent, de novo pathogenic variant in ARPC4 disrupts actin filament formation and causes microcephaly and speech delay.
Laboy Cintron D, Muir AM, Scott A, McDonald M, Monaghan KG, Santiago-Sim T, Wentzensen IM, De Luca C, Italian Undiagnosed Diseases Network, Brancati F, et al. HGG Adv. 2022 Jan 13; 3(1):100072. Epub 2021 Nov 25.
ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis. [J Cell Biochem. 2020]
ARPC4 promotes bladder cancer cell invasion and is associated with lymph node metastasis.
Xu N, Qu GY, Wu YP, Lin YZ, Chen DN, Li XD, Chen SH, Huang JB, Zheng QS, Xue XY, et al. J Cell Biochem. 2020 Jan; 121(1):231-243. Epub 2019 Jun 12.
Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages. [PLoS One. 2013]
Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages.
Ghosh A, Tousif S, Bhattacharya D, Samuchiwal SK, Bhalla K, Tharad M, Kumar S, Prakash P, Kumar P, Das G, et al. PLoS One. 2013; 8(7):e69949. Epub 2013 Jul 22.

RefSeq protein isoforms
See 4 reference sequence protein isoforms for the ARPC4 gene.

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P59998 [Domain Mapping of Disease Mut...]
P59998
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, partial (chloropl...
ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit, partial (chloroplast) [Humulus lupulus]
gi|2618953770|gb|WOZ48097.1|

Protein
Homo sapiens unc-51 like kinase 3 (ULK3), transcript variant 6, non-coding RNA
Homo sapiens unc-51 like kinase 3 (ULK3), transcript variant 6, non-coding RNA
gi|1701215603|ref|NR_104309.3|

Nucleotide

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Protein