RecName: Full=Signal peptide peptidase-like 2A; Short=SPP-like 2A; Sho - Protein

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Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74. [Biochem J. 2016]
Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74.
Hüttl S, Helfrich F, Mentrup T, Held S, Fukumori A, Steiner H, Saftig P, Fluhrer R, Schröder B. Biochem J. 2016 May 15; 473(10):1405-22. Epub 2016 Mar 17.
Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells. [Biochem Biophys Res Commun. 2014]
Signal-peptide-peptidase-like 2a is required for CD74 intramembrane proteolysis in human B cells.
Schneppenheim J, Hüttl S, Kruchen A, Fluhrer R, Müller I, Saftig P, Schneppenheim R, Martin CL, Schröder B. Biochem Biophys Res Commun. 2014 Aug 15; 451(1):48-53. Epub 2014 Jul 15.
A novel homozygous p.R1105X mutation of the AP4E1 gene in twins with hereditary spastic paraplegia and mycobacterial disease. [PLoS One. 2013]
A novel homozygous p.R1105X mutation of the AP4E1 gene in twins with hereditary spastic paraplegia and mycobacterial disease.
Kong XF, Bousfiha A, Rouissi A, Itan Y, Abhyankar A, Bryant V, Okada S, Ailal F, Bustamante J, Casanova JL, et al. PLoS One. 2013; 8(3):e58286. Epub 2013 Mar 5.

RefSeq protein isoforms
See 8 reference sequence protein isoforms for the SPPL2A gene.

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Q8TCT8 [Domain Mapping of Disease Mut...]
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Protein