RecName: Full=Glutathione-specific gamma-glutamylcyclotransferase 2; S - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Structural and Functional Analyses of Human ChaC2 in Glutathione Metabolism. [Biomolecules. 2019]
Structural and Functional Analyses of Human ChaC2 in Glutathione Metabolism.
Nguyen YTK, Park JS, Jang JY, Kim KR, Vo TTL, Kim KW, Han BW. Biomolecules. 2019 Dec 24; 10(1). Epub 2019 Dec 24.
CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response. [Cell Death Dis. 2017]
CHAC2, downregulated in gastric and colorectal cancers, acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response.
Liu S, Fei W, Shi Q, Li Q, Kuang Y, Wang C, He C, Hu X. Cell Death Dis. 2017 Aug 24; 8(8):e3009. Epub 2017 Aug 24.
E3 ubiquitin ligase RNF148 functions as an oncogene in colorectal cancer by ubiquitination-mediated degradation of CHAC2. [Carcinogenesis. 2024]
E3 ubiquitin ligase RNF148 functions as an oncogene in colorectal cancer by ubiquitination-mediated degradation of CHAC2.
Liu S, Zhuo L, Chen L, He Y, Chen X, Zhang H, Zhou Y, Ni Z, Zhao S, Hu X. Carcinogenesis. 2024 Apr 12; 45(4):247-261.

RefSeq protein isoforms
See 2 reference sequence protein isoforms for the CHAC2 gene.

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed

Q8WUX2 [Domain Mapping of Disease Mut...]
Q8WUX2
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

ChaC, cation transport regulator homolog 2 (E. coli) [Homo sapiens]
ChaC, cation transport regulator homolog 2 (E. coli) [Homo sapiens]
gi|17512585|gb|AAH19239.1|

Protein
Homo sapiens cDNA FLJ12441 fis, clone NT2RM1000132, highly similar to NADH-ubiqu...
Homo sapiens cDNA FLJ12441 fis, clone NT2RM1000132, highly similar to NADH-ubiquinone oxidoreductase 13 kDa-A subunit, mitochondrial precursor (EC 1.6.5.3)
gi|10433927|dbj|AK022503.1|

Nucleotide
602671962F1 NIH_MGC_96 Homo sapiens cDNA clone IMAGE:4794759 5', mRNA sequence
602671962F1 NIH_MGC_96 Homo sapiens cDNA clone IMAGE:4794759 5', mRNA sequence
gi|13982528|gnl|dbEST|8471503|gb|BG 2.1|

Nucleotide
PREDICTED: Rattus norvegicus synaptojanin 1 (Synj1), transcript variant X35, mRN...
PREDICTED: Rattus norvegicus synaptojanin 1 (Synj1), transcript variant X35, mRNA
gi|2678885821|ref|XM_039088706.2|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Protein