RecName: Full=Endothelial PAS domain-containing protein 1; Short=EPAS- - Protein

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders. [Sci Adv. 2024]
Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders.
Lawrence ES, Gu W, Bohlender RJ, Anza-Ramirez C, Cole AM, Yu JJ, Hu H, Heinrich EC, O'Brien KA, Vasquez CA, et al. Sci Adv. 2024 Feb 9; 10(6):eadj5661. Epub 2024 Feb 9.
EPAS1-mutated paragangliomas associated with haemoglobin disorders. [Br J Haematol. 2024]
EPAS1-mutated paragangliomas associated with haemoglobin disorders.
Mancini M, Buffet A, Porte B, Amar L, Lussey-Lepoutre C, Crinière L, Baudin E, Meatchi T, Gimenez-Roqueplo AP, Favier J, et al. Br J Haematol. 2024 Mar; 204(3):1054-1060. Epub 2024 Jan 9.
Hypoxia-inducible factor 2α protein and mRNA expression correlate with histomorphological features in clear cell renal cell carcinoma. [Pathol Res Pract. 2023]
Hypoxia-inducible factor 2α protein and mRNA expression correlate with histomorphological features in clear cell renal cell carcinoma.
Pham T, Ohe C, Yoshida T, Nakamoto T, Kinoshita H, Tsuta K. Pathol Res Pract. 2023 Nov; 251:154841. Epub 2023 Oct 2.

RefSeq genomic sequence
See the genomic reference sequence for the EPAS1 gene (NG_016000.1).

PubMed
PubMed articles cited by protein sequence record
Taxonomy
Taxonomy sequences associated with protein record
BioAssay by Target (Summary)
BioAssay by Target (Summary)
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Full text in PMC
Free full text articles in PMC
Gene
Link to related Genes
Identical Structures
3D structures for identical protein sequences
OMIM
OMIM records associated with protein sequence
Protein (RefSeq)
Protein gi (UniProtKB) to protein gi (refseq)
PubMed (Weighted)
Links to pubmed
Related Structures (List)
List of related structures

Q99814 [Domain Mapping of Disease Mut...]
Q99814
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome

Homo sapiens mucin 16, cell surface associated (MUC16), RefSeqGene on chromosome...
Homo sapiens mucin 16, cell surface associated (MUC16), RefSeqGene on chromosome 19
gi|1209185424|ref|NG_055257.1|

Nucleotide
Homo sapiens plasminogen like B2 (PLGLB2), mRNA
Homo sapiens plasminogen like B2 (PLGLB2), mRNA
gi|123702173|ref|NM_002665.4|

Nucleotide
Mus musculus RIKEN cDNA 2810452K22 gene, mRNA (cDNA clone MGC:28072 IMAGE:371002...
Mus musculus RIKEN cDNA 2810452K22 gene, mRNA (cDNA clone MGC:28072 IMAGE:3710025), complete cds
gi|18256893|gb|BC021867.1|

Nucleotide
Heart Valve Prolapse
Heart Valve Prolapse
Downward displacement of any one of the HEART VALVES from its normal position. This usually results in failed valve closure.<br/>Year introduced: 1991

MeSH
Bicuspid Aortic Valve Disease
Bicuspid Aortic Valve Disease
Congenital heart valve defects where the AORTIC VALVE has two instead of normal three cusps. It is often associated with AORTIC REGURGITATION and AORTIC INSUFFICIENCY....<br/>Year introduced: 2021

MeSH

Your browsing activity is empty.

Activity recording is turned off.

Protein