RecName: Full=E3 ubiquitin-protein ligase pellino homolog 2; Short=Pel - Protein

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K(+) regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages. [FEBS Lett. 2021]
K(+) regulates relocation of Pellino-2 to the site of NLRP3 inflammasome activation in macrophages.
Cristea I, Bruland O, Rødahl E, Bredrup C. FEBS Lett. 2021 Oct; 595(19):2437-2446. Epub 2021 Sep 1.
Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control. [J Biol Chem. 2012]
Pellino 2 is critical for Toll-like receptor/interleukin-1 receptor (TLR/IL-1R)-mediated post-transcriptional control.
Kim TW, Yu M, Zhou H, Cui W, Wang J, DiCorleto P, Fox P, Xiao H, Li X. J Biol Chem. 2012 Jul 20; 287(30):25686-95. Epub 2012 Jun 5.
Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1. [Structure. 2008]
Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.
Lin CC, Huoh YS, Schmitz KR, Jensen LE, Ferguson KM. Structure. 2008 Dec 10; 16(12):1806-16.

RefSeq protein isoforms
See 13 reference sequence protein isoforms for the PELI2 gene.

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Q9HAT8 [Domain Mapping of Disease Mut...]
Q9HAT8
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

MULTISPECIES: DUF3021 family protein [Salmonella]
MULTISPECIES: DUF3021 family protein [Salmonella]
gi|447048310|ref|WP_001125566.1|

Protein
dystrophin C-terminal region (32 AA), partial [Homo sapiens]
dystrophin C-terminal region (32 AA), partial [Homo sapiens]
gi|30931|emb|CAA33246.1|

Protein
NF-kappa-B essential modulator isoform X3 [Mus musculus]
NF-kappa-B essential modulator isoform X3 [Mus musculus]
gi|569009769|ref|XP_006527915.1|

Protein
UI-H-BI0-aab-b-01-0-UI.s1 NCI_CGAP_Sub1 Homo sapiens cDNA clone IMAGE:2708665 3'...
UI-H-BI0-aab-b-01-0-UI.s1 NCI_CGAP_Sub1 Homo sapiens cDNA clone IMAGE:2708665 3', mRNA sequence
gi|5862566|gnl|dbEST|3142797|gb|AW0 .1|

Nucleotide

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Protein