RecName: Full=Tyrosine--tRNA ligase, mitochondrial; AltName: Full=Tyro - Protein

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Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy. [Hum Mol Genet. 2023]
Nuclear modifier YARS2 allele correction restored retinal ganglion cells-specific deficiencies in Leber's hereditary optic neuropathy.
Chen JR, Chen C, Chen J, Ji Y, Lian Y, Zhang J, Yu J, Li XY, Qu J, Guan MX. Hum Mol Genet. 2023 Apr 20; 32(9):1539-1551.
Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression. [Cancer Biol Ther. 2022]
Targeting mitochondrial tyrosyl-tRNA synthetase YARS2 suppresses colorectal cancer progression.
Fang Q, Lin J, Gao L, Pan R, Zheng X. Cancer Biol Ther. 2022 Dec 31; 23(1):1-8.
Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNA(Ser(UCN)) 7511A>G mutation. [J Biol Chem. 2019]
Contribution of a mitochondrial tyrosyl-tRNA synthetase mutation to the phenotypic expression of the deafness-associated tRNA(Ser(UCN)) 7511A>G mutation.
Fan W, Zheng J, Kong W, Cui L, Aishanjiang M, Yi Q, Wang M, Cang X, Tang X, Chen Y, et al. J Biol Chem. 2019 Dec 13; 294(50):19292-19305. Epub 2019 Nov 4.

RefSeq genomic sequence
See the genomic reference sequence for the YARS2 gene (NG_028122.1).
RefSeq protein
See the reference protein sequence for tyrosine--tRNA ligase, mitochondrial precursor (NP_001035526.1).

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Q9Y2Z4 [Domain Mapping of Disease Mut...]
Q9Y2Z4
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Tyrosine--tRNA ligase, mitochondrial; AltName: Full=Tyrosyl-tRNA s...
RecName: Full=Tyrosine--tRNA ligase, mitochondrial; AltName: Full=Tyrosyl-tRNA synthetase; Short=TyrRS; Flags: Precursor
gi|50401709|sp|Q9Y2Z4.2|SYYM_HUMAN

Protein
Chain F, General control protein GCN4 and Tropomyosin alpha-1 chain
Chain F, General control protein GCN4 and Tropomyosin alpha-1 chain
gi|185177670|pdb|2Z5I|F

Protein

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