DNA polymerase epsilon catalytic subunit, partial [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway. [Cell Death Dis. 2024]
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.
Tang M, Yin S, Zeng H, Huang A, Huang Y, Hu Z, Shah AR, Zhang S, Li H, Chen G. Cell Death Dis. 2024 Jan 18; 15(1):69. Epub 2024 Jan 18.
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer. [In Vivo. 2024]
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer.
Kitazono I, Akahane T, Yokoyama S, Kubota E, Nishida-Kirita Y, Noguchi H, Murakami M, Yanazume S, Kobayashi H, Tanimoto A. In Vivo. 2024 Jan-Feb; 38(1):321-333.
Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants. [Life Sci Alliance. 2024]
Exploring the basis of heterogeneity of cancer aggressiveness among the mutated POLE variants.
Selves J, de Castro E Gloria H, Brunac AC, Saffi J, Guimbaud R, Brousset P, Hoffmann JS. Life Sci Alliance. 2024 Jan; 7(1). Epub 2023 Oct 27.

RefSeq genomic sequence
See the genomic reference sequence for the POLE gene (NG_033840.1).
RefSeq protein isoforms
See 11 reference sequence protein isoforms for the POLE gene.

Your browsing activity is empty.

Activity recording is turned off.

Protein