DNA ligase 3 isoform X4 [Homo sapiens]

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Myopathic mitochondrial DNA depletion syndrome associated with biallelic variants in LIG3. [Brain. 2021]
Myopathic mitochondrial DNA depletion syndrome associated with biallelic variants in LIG3.
Invernizzi F, Legati A, Nasca A, Lamantea E, Garavaglia B, Gusic M, Kopajtich R, Prokisch H, Zeviani M, Lamperti C, et al. Brain. 2021 Oct 22; 144(9):e74.
LIG3 gene polymorphisms and risk of gastric cancer in a Southern Chinese population. [Gene. 2019]
LIG3 gene polymorphisms and risk of gastric cancer in a Southern Chinese population.
Hua RX, Zhuo Z, Zhu J, Zhang SD, Xue WQ, Li XZ, He J, Jia WH. Gene. 2019 Jul 15; 705:90-94. Epub 2019 Apr 26.
Polymorphism rs1052536 in Base Excision Repair Gene Is a Risk Factor in a High-Risk Area of Neural Tube Defects in China. [Med Sci Monit. 2018]
Polymorphism rs1052536 in Base Excision Repair Gene Is a Risk Factor in a High-Risk Area of Neural Tube Defects in China.
Li G, Wang X, Wang X, Guan Z, Guo J, Wang F, Zhang J, Niu B, Zhang T, Wang J, et al. Med Sci Monit. 2018 Jul 19; 24:5015-5026. Epub 2018 Jul 19.

RefSeq genomic sequence
See the genomic reference sequence for the LIG3 gene (NG_029221.2).
RefSeq mRNA
See reference mRNA sequence for the LIG3 gene (XM_017024624.2).
RefSeq protein isoforms
See 18 reference sequence protein isoforms for the LIG3 gene.

BioProject
Proteins related to BioProjects
Nucleotide
Nucleotide sequence from coding region
Taxonomy
Taxonomy sequences associated with protein record
BioSystems
BioSystems
CDD Search Results
Display conserved domains within a protein
Conserved Domains (Concise)
Link to a concise list of conserved domains in a protein
Conserved Domains (Full)
Link to conserved domains within a protein
Domain Relatives
Display proteins with similar conserved domain architecture
Encoding mRNA
Link from protein to encoding mRNA
Gene
Link to related Genes
Genome
Genome record encoding protein sequence
Identical Structures
3D structures for identical protein sequences
Protein (UniProtKB)
Protein gi (refseq) to protein gi (UniProtKB)
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed
SNP
Related SNPs

PREDICTED: Homo sapiens myosin VIIB (MYO7B), transcript variant X9, mRNA
PREDICTED: Homo sapiens myosin VIIB (MYO7B), transcript variant X9, mRNA
gi|2462573491|ref|XM_054342168.1|

Nucleotide
Homo sapiens cellular communication network factor 2 (CCN2), mRNA
Homo sapiens cellular communication network factor 2 (CCN2), mRNA
gi|1844084029|ref|NM_001901.4|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Protein