neuronal acetylcholine receptor subunit alpha-2 isoform X1 [Homo sapie - Protein

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Identify Conserved Domains
View conserved domains detected in this protein sequence using CD-search.

Genome-wide association study implicates CHRNA2 in cannabis use disorder. [Nat Neurosci. 2019]
Genome-wide association study implicates CHRNA2 in cannabis use disorder.
Demontis D, Rajagopal VM, Thorgeirsson TE, Als TD, Grove J, Leppälä K, Gudbjartsson DF, Pallesen J, Hjorthøj C, Reginsson GW, et al. Nat Neurosci. 2019 Jul; 22(7):1066-1074. Epub 2019 Jun 17.
Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer. [Proc Natl Acad Sci U S A. 2016]
Crystal structure of a human neuronal nAChR extracellular domain in pentameric assembly: Ligand-bound α2 homopentamer.
Kouvatsos N, Giastas P, Chroni-Tzartou D, Poulopoulou C, Tzartos SJ. Proc Natl Acad Sci U S A. 2016 Aug 23; 113(34):9635-40. Epub 2016 Aug 4.
Mutation of CHRNA2 in a family with benign familial infantile seizures: Potential role of nicotinic acetylcholine receptor in various phenotypes of epilepsy. [Epilepsia. 2015]
Mutation of CHRNA2 in a family with benign familial infantile seizures: Potential role of nicotinic acetylcholine receptor in various phenotypes of epilepsy.
Trivisano M, Terracciano A, Milano T, Cappelletti S, Pietrafusa N, Bertini ES, Vigevano F, Specchio N. Epilepsia. 2015 May; 56(5):e53-7. Epub 2015 Apr 3.

RefSeq genomic sequence
See the genomic reference sequence for the CHRNA2 gene (NG_015827.1).
RefSeq mRNA
See reference mRNA sequence for the CHRNA2 gene (XM_054359683.1).
RefSeq protein isoforms
See 12 reference sequence protein isoforms for the CHRNA2 gene.

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Protein