dihydroorotate dehydrogenase [Plasmodium falciparum 3D7]

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Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria. [J Med Chem. 2020]
Lead Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series for the Treatment of Malaria.
Kokkonda S, Deng X, White KL, El Mazouni F, White J, Shackleford DM, Katneni K, Chiu FCK, Barker H, McLaren J, et al. J Med Chem. 2020 May 14; 63(9):4929-4956. Epub 2020 Apr 16.
Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase. [ACS Med Chem Lett. 2017]
Discovery of Antimalarial Azetidine-2-carbonitriles That Inhibit P. falciparum Dihydroorotate Dehydrogenase.
Maetani M, Kato N, Jabor VAP, Calil FA, Nonato MC, Scherer CA, Schreiber SL. ACS Med Chem Lett. 2017 Apr 13; 8(4):438-442. Epub 2017 Feb 27.
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum. [Sci Rep. 2016]
Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum.
Dickerman BK, Elsworth B, Cobbold SA, Nie CQ, McConville MJ, Crabb BS, Gilson PR. Sci Rep. 2016 Nov 22; 6:37502. Epub 2016 Nov 22.

RefSeq mRNA
See reference mRNA sequence for the PF3D7_0603300 gene (XM_960930.1).

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GMP synthase [glutamine-hydrolyzing] [Plasmodium falciparum 3D7]
GMP synthase [glutamine-hydrolyzing] [Plasmodium falciparum 3D7]
gi|124802227|ref|XP_001347408.1|

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