RecName: Full=E3 ubiquitin-protein ligase RNF216; AltName: Full=RING f - Protein

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Whole-Exome Sequencing Identified a Novel Mutation in RNF216 in a Family with Gordon Holmes Syndrome. [J Mol Neurosci. 2022]
Whole-Exome Sequencing Identified a Novel Mutation in RNF216 in a Family with Gordon Holmes Syndrome.
Chen KL, Wang H, Zhao GX, Wei L, Huang YY, Chen SD, Sun J, Dong Q, Cui M, Yu JT. J Mol Neurosci. 2022 Apr; 72(4):691-694. Epub 2022 Jan 28.
Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. [Mol Cell. 2022]
Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216.
Cotton TR, Cobbold SA, Bernardini JP, Richardson LW, Wang XS, Lechtenberg BC. Mol Cell. 2022 Feb 3; 82(3):598-615.e8. Epub 2022 Jan 7.
RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy. [Oncotarget. 2016]
RNF216 contributes to proliferation and migration of colorectal cancer via suppressing BECN1-dependent autophagy.
Wang H, Wang Y, Qian L, Wang X, Gu H, Dong X, Huang S, Jin M, Ge H, Xu C, et al. Oncotarget. 2016 Aug 9; 7(32):51174-51183.

RefSeq genomic sequence
See the genomic reference sequence for the RNF216 gene (NG_029374.2).
RefSeq protein isoforms
See 18 reference sequence protein isoforms for the RNF216 gene.

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Q9NWF9 [Domain Mapping of Disease Mut...]
Q9NWF9
Domain Mapping of Disease Mutations
Transcript/Protein Information [PANTHER Classification System]
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Reactome [Reactome]
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reagents [ExactAntigen/Labome]
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RecName: Full=E3 ubiquitin-protein ligase RNF216; AltName: Full=RING finger prot...
RecName: Full=E3 ubiquitin-protein ligase RNF216; AltName: Full=RING finger protein 216; AltName: Full=RING-type E3 ubiquitin transferase RNF216; AltName: Full=Triad domain-containing protein 3; AltName: Full=Ubiquitin-conjugating enzyme 7-interacting protein 1; AltName: Full=Zinc finger protein inhibiting NF-kappa-B
gi|57015417|sp|Q9NWF9.3|RN216_HUMAN

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