RecName: Full=Serine protease HTRA2, mitochondrial; AltName: Full=High - Protein

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Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway. [Commun Biol. 2024]
Cytosolic retention of HtrA2 during mitochondrial protein import stress triggers the DELE1-HRI pathway.
Bi PY, Killackey SA, Schweizer L, Arnoult D, Philpott DJ, Girardin SE. Commun Biol. 2024 Mar 30; 7(1):391. Epub 2024 Mar 30.
Role of high-temperature requirement serine protease A 2 in rheumatoid inflammation. [Arthritis Res Ther. 2023]
Role of high-temperature requirement serine protease A 2 in rheumatoid inflammation.
Jeong GH, Nam MK, Hur W, Heo S, Lee S, Choi E, Park JH, Park Y, Kim WU, Rhim H, et al. Arthritis Res Ther. 2023 Jun 7; 25(1):96. Epub 2023 Jun 7.
A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells. [Mol Oncol. 2022]
A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells.
Hammer L, Levin-Salomon V, Yaeli-Slonim N, Weiss M, Dekel-Bird NP, Olender T, Porat Z, Winograd-Katz S, Savidor A, Levin Y, et al. Mol Oncol. 2022 Mar; 16(6):1365-1383. Epub 2022 Feb 16.

RefSeq genomic sequence
See the genomic reference sequence for the HTRA2 gene (NG_033037.1).
RefSeq genomic sequence
See the genomic reference sequence for the HTRA2 gene (NG_012163.1).
RefSeq protein isoforms
See 4 reference sequence protein isoforms for the HTRA2 gene.

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O43464 [Domain Mapping of Disease Mut...]
O43464
Domain Mapping of Disease Mutations
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF) [MODBASE, Database of Comparat...]
MODBASE, Database of Comparative Protein Structure Models (Sali Lab/UCSF)
Transcript/Protein Information [PANTHER Classification System]
Transcript/Protein Information
PANTHER Classification System
Reactome [Reactome]
Reactome
reagents [ExactAntigen/Labome]
reagents
ExactAntigen/Labome
reagent reviews [ExactAntigen/Labome]
reagent reviews
ExactAntigen/Labome
Evolutionary Trace of Functional Site [Evolutionary Trace of Functio...]
Evolutionary Trace of Functional Site

RecName: Full=Serine protease HTRA2, mitochondrial; AltName: Full=High temperatu...
RecName: Full=Serine protease HTRA2, mitochondrial; AltName: Full=High temperature requirement protein A2; Short=HtrA2; AltName: Full=Omi stress-regulated endoprotease; AltName: Full=Serine protease 25; AltName: Full=Serine proteinase OMI; Flags: Precursor
gi|17376879|sp|O43464.2|HTRA2_HUMAN

Protein
BioProject Links for Protein (Select 657613534) (1)
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Taxonomy Links for Nucleotide (Select 529603534) (1)
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