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TPM domain-containing protein
This family was first named TPM domain after its founding proteins: TLP18.3, Psb32 and MOLO-1. In Arabidopsis, this domain is called the thylakoid acid phosphatase -TAP - domain and has a Rossmann-like fold [1]. In plants, the family resides in the thylakoid lumen attached to the outer membrane of the chloroplast/plastid. It is active in the photosystem II [2,3]. [1]. 21908686. Structural and Functional Assays of AtTLP18.3 Identify Its Novel. Acid Phosphatase Activity in Thylakoid Lumen.. Wu HY, Liu MS, Lin TP, Cheng YS;. Plant physiol. 2011;9:0-0.. [2]. 17576201. TLP18.3, a novel thylakoid lumen protein regulating photosystem. II repair cycle.. Sirpio S, Allahverdiyeva Y, Suorsa M, Paakkarinen V, Vainonen J,. Battchikova N, Aro EM;. Biochem J. 2007;406:415-425.. [3]. 21653280. The Psb32 protein aids in repairing photodamaged photosystem II. in the cyanobacterium Synechocystis 6803.. Wegener KM, Bennewitz S, Oelmuller R, Pakrasi HB;. Mol Plant. 2011;4:1052-1061. (from Pfam)
TPM (TLP18.3, Psb32 and MOLO-1) domain-containing protein may have phosphatase activity, similar to Escherichia coli YgcG and Bacillus subtilis YdjH
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