Protein Family Models for Protein (Select 1033020275) - Protein Family Models

Select item 4111171.

Members of this family catalyse the first step in aromatic amino acid biosynthesis from chorismate. E-coli has three related synthetases, which are inhibited by different aromatic amino acids. This family also includes KDSA which has very similar catalytic activity but is involved in the first step of liposaccharide biosynthesis. The enzyme is also part of the shikimate pathway, EC:2.5.1.54. [1]. 10425687. Crystal structure of phenylalanine-regulated. 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from. Escherichia coli.. Shumilin IA, Kretsinger RH, Bauerle RH;. Structure Fold Des 1999;7:865-875. (from Pfam)

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Date:: 2024-08-14

Family Accession:: NF012991.5
Method:: HMM

Select item 3886132.

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Family Accession:

Select item 3468773.

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Family Accession:

Select item 544584.

3-deoxy-7-phosphoheptulonate synthase AroH

3-deoxy-7-phosphoheptulonate synthase AroH catalyzes stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP)

Date:: 2023-02-16

Family Accession:: 10014073
Method:: Sparcle

Select item 313915.

Trp-sensitive 3-deoxy-7-phosphoheptulonate synthase AroH

Tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate

Gene:: aroH

Date:: 2020-10-26

Family Accession:: NF009396.0
Method:: HMM

Select item 308606.

3-deoxy-7-phosphoheptulonate synthase

Catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive

Date:: 2020-10-26

Family Accession:: NF009395.0
Method:: HMM

Select item 163697.

3-deoxy-7-phosphoheptulonate synthase

3-deoxy-7-phosphoheptulonate synthase is involved in the biosynthesis of chorismate, the final common intermediate in the biosynthesis of phenylalanine, tyrosine and tryptophan (the aromatic amino acids) as well as menaquinone, ubiquinone, and other products. Three isozymes in E. coli K-12 are designated AroF, AroG, and AroH.

GO Terms:

Biological Process:: aromatic amino acid family biosynthetic process (GO:0009073)

Molecular Function:: aldehyde-lyase activity (GO:0016832)

Date:: 2024-06-10

Family Accession:: TIGR00034.1
Method:: HMM

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