Protein Family Models for Protein (Select 1055298883) - Protein Family Models

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Links from Protein

Items: 6

Select item 4174611.

FabA-like domain

This enzyme domain has a HotDog fold. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF019589.5
Method:: HMM

Select item 3962922.

new record, indexing in progress

Family Accession:

Select item 3520723.

new record, indexing in progress

Family Accession:

Select item 1967724.

3-hydroxyacyl-ACP dehydratase FabZ

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP

Date:: 2023-02-21

Family Accession:: 10791549
Method:: Sparcle

Select item 1420645.

3-hydroxyacyl-ACP dehydratase FabZ

This enzyme, FabZ, shows overlapping substrate specificity with FabA with regard to chain length in fatty acid biosynthesis. FabZ works preferentially on shorter chains and is often designated (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase, although its actual specificity is broader. Unlike FabA, FabZ does not function as an isomerase and cannot initiate unsaturated fatty acid biosynthesis. However, only FabZ can act during the elongation of unsaturated fatty acid chains.

Gene:: fabZ

GO Terms:

Biological Process:: fatty acid biosynthetic process (GO:0006633)

Molecular Function:: hydro-lyase activity (GO:0016836)

Molecular Function:: (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity (GO:0019171)

Date:: 2024-06-21

Family Accession:: TIGR01750.1
Method:: HMM

Select item 159696.

3-hydroxyacyl-ACP dehydratase FabZ

Essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP