Protein Family Models for Protein (Select 1222443639) - Protein Family Models

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Select item 4110981.

aminotransferase class V-fold PLP-dependent enzyme

This domain is found in amino transferases, and other enzymes including cysteine desulphurase EC:4.4.1.-. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF012488.5
Method:: HMM

Select item 4110372.

aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme

GO Terms:

Biological Process:: biosynthetic process (GO:0009058)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Date:: 2024-08-14

Family Accession:: NF012382.5
Method:: HMM

Select item 4110193.

PLP-dependent transferase

This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor. [1]. 8831789. Crystal structure of the pyridoxal-5'-phosphate dependent. cystathionine beta-lyase from Escherichia coli at 1.83 A.. Clausen T, Huber R, Laber B, Pohlenz HD, Messerschmidt A;. J Mol Biol 1996;262:202-224.. [2]. 9843488. Crystal structure of Escherichia coli cystathionine. gamma-synthase at 1.5 A resolution.. Clausen T, Huber R, Prade L, Wahl MC, Messerschmidt A;. EMBO J 1998;17:6827-6838. (from Pfam)

GO Terms:

Biological Process:: transsulfuration (GO:0019346)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Date:: 2024-08-14

Family Accession:: NF013237.5
Method:: HMM

Select item 4110184.

DegT/DnrJ/EryC1/StrS family aminotransferase

The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyses the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin [1]. [1]. 9238101. Identification of stsC, the gene encoding the. L-glutamine:scyllo-inosose aminotransferase from. streptomycin-producing Streptomycetes.. Ahlert J, Distler J, Mansouri K, Piepersberg W;. Arch Microbiol 1997;168:102-113. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF013227.5
Method:: HMM

Select item 3887515.

new record, indexing in progress

Family Accession:

Select item 3887106.

new record, indexing in progress

Family Accession:

Select item 3884947.

new record, indexing in progress

Family Accession:

Select item 3883598.

new record, indexing in progress

Family Accession:

Select item 3482689.

new record, indexing in progress

Family Accession:

Select item 34816910.

new record, indexing in progress

Family Accession:

Select item 34810611.

new record, indexing in progress

Family Accession:

Select item 34738012.

new record, indexing in progress

Family Accession:

Select item 31678313.

new record, indexing in progress

Family Accession:

Select item 31618714.

new record, indexing in progress

Family Accession:

Select item 31612715.

new record, indexing in progress

Family Accession:

Select item 31553516.

new record, indexing in progress

Family Accession:

Select item 14298717.

cysteine desulfurase-like protein

This HMM describes a subfamily of probable pyridoxal phosphate-dependent enzymes in the aminotransferase class V family (PF00266). The most closely related characterized proteins are active as cysteine desulfurases, selenocysteine lyases, or both; some are involved in FeS cofactor biosynthesis and are designated NifS. An active site Cys residue present in those sequences, in motifs resembling GHHC or GSAC, is not found in this family. The function of members of this family is unknown, but seems unlike to be as an aminotransferase.

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2021-08-24

Family Accession:: TIGR01976.1
Method:: HMM

Select item 4477518.

new record, indexing in progress

Family Accession:

Select item 4398219.

new record, indexing in progress

Family Accession:

Select item 3959420.

new record, indexing in progress

Family Accession:

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