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GTP cyclohydrolase I
This family includes GTP cyclohydrolase enzymes and a family of related bacterial proteins including Swiss:Q46920. [1]. 7663943. Atomic structure of GTP cyclohydrolase I.. Nar H, Huber R, Meining W, Schmid C, Weinkauf S, Bacher A;. Structure 1995;3:459-466. (from Pfam)
GTP cyclohydrolase I FolE
GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate
alternate names: Punch (Drosophila), GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects.
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