Protein Family Models

These sequences are functionally identified as members of the adenylate cyclase family, which catalyses the conversion of ATP to 3',5'-cyclic AMP and pyrophosphate. Six distinct non-homologous classes of AC have been identified. The structure of three classes of adenylyl cyclases have been solved [3]. [1]. 9642185. Aeromonas hydrophila adenylyl cyclase 2: a new class of adenylyl. cyclases with thermophilic properties and sequence similarities. to proteins from hyperthermophilic archaebacteria.. Sismeiro O, Trotot P, Biville F, Vivares C, Danchin A;. J Bacteriol 1998;180:3339-3344.. [2]. 12456267. The catalytic domains of thiamine triphosphatase and CyaB-like. adenylyl cyclase define a novel superfamily of domains that bind. organic phosphates.. Iyer LM, Aravind L;. BMC Genomics 2002;3:33-33.. [3]. 16905149. Structure of the class IV adenylyl cyclase reveals a novel fold.. Gallagher DT, Smith NN, Kim SK, Heroux A, Robinson H, Reddy PT;. J Mol Biol. 2006;362:114-122.. [4]. 16511301. Crystallization of the class IV adenylyl cyclase from Yersinia. pestis.. Smith N, Kim SK, Reddy PT, Gallagher DT;. Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006;62:200-204. (from Pfam)

Date:

2024-08-14

inorganic triphosphatase catalyzes the hydrolysis of inorganic or nucleoside-linked triphosphate-containing substrates

Date:

2017-10-13