Protein Family Models

This is the C-terminal domain of the 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme. This domain forms a left handed super-helix. (from Pfam)

Date:

2024-08-14

This domain is found to the C-terminus of Pfam:PF02670 domains in bacterial and plant 1-deoxy-D-xylulose 5-phosphate reductoisomerases which catalyse the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH [1]. [1]. 9707569. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the. formation of 2-C-methyl-D-erythritol 4-phosphate in an. alternative nonmevalonate pathway for terpenoid biosynthesis.. Takahashi S, Kuzuyama T, Watanabe H, Seto H;. Proc Natl Acad Sci U S A 1998;95:9879-9884. (from Pfam)

Date:

2024-08-14

This is a family of 1-deoxy-D-xylulose 5-phosphate reductoisomerases. This enzyme catalyses the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate in the presence of NADPH [1]. This reaction is part of the terpenoid biosynthesis pathway. [1]. 9707569. A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the. formation of 2-C-methyl-D-erythritol 4-phosphate in an. alternative nonmevalonate pathway for terpenoid biosynthesis.. Takahashi S, Kuzuyama T, Watanabe H, Seto H;. Proc Natl Acad Sci U S A 1998;95:9879-9884. (from Pfam)

Date:

2024-08-14

1-deoxy-D-xylulose-5-phosphate reductoisomerase catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)

Date:

2023-03-01

1-deoxy-D-xylulose 5-phosphate is converted to 2-C-methyl-D-erythritol 4-phosphate in the presence of NADPH. It is involved in the synthesis of isopentenyl diphosphate (IPP), a basic building block in isoprenoid, thiamin, and pyridoxal biosynthesis.

Gene:

dxr

Date:

2024-06-04