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phosphatase PAP2 family protein
This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases [1,2] that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids. [1]. 9041652. Identification of a novel phosphatase sequence motif.. Stukey J, Carman GM;. Protein Sci 1997;6:469-472.. [2]. 9260289. An unexpected structural relationship between integral membrane. phosphatases and soluble haloperoxidases.. Neuwald AF;. Protein Sci 1997;6:1764-1767.. [3]. 8552646. X-ray structure of a vanadium-containing enzyme:. chloroperoxidase from the fungus Curvularia inaequalis.. Messerschmidt A, Wever R;. Proc Natl Acad Sci U S A 1996;93:392-396. (from Pfam)
type 2 phosphatidic acid phosphatase (PAP2) family protein similar to Bacillus subtilis phosphatidylglycerophosphatase B that catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol
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