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Links from Protein

Items: 20

1.

DNA polymerase III subunit alpha, C-terminal domain

Date:
2024-08-14

Family Accession:
NF044651.2
Method:
HMM

2.

Bacterial DNA polymerase III alpha subunit finger domain

Date:
2024-08-14

Family Accession:
NF036968.5
Method:
HMM

3.

Helix-hairpin-helix motif

The HHH domain is a short DNA-binding domain [1]. [1]. 8692686. The helix-hairpin-helix DNA-binding motif: a structural basis. for non-sequence-specific recognition of DNA.. Doherty AJ, Serpell LC, Ponting CP;. Nucleic Acids Res 1996;24:2488-2497. (from Pfam)

Date:
2024-08-14

Family Accession:
NF025930.5
Method:
HMM

4.

Bacterial DNA polymerase III alpha NTPase domain

GO Terms:
Biological Process:
DNA replication (GO:0006260)
Molecular Function:
3'-5' exonuclease activity (GO:0008408)
Date:
2024-08-14

Family Accession:
NF019353.5
Method:
HMM

5.

PHP domain-containing protein

The PHP (Polymerase and Histidinol Phosphatase) domain is a putative phosphoesterase domain. [1]. 9685491. Phosphoesterase domains associated with DNA polymerases of. diverse origins.. Aravind L, Koonin EV;. Nucleic Acids Res 1998;26:3746-3752. (from Pfam)

GO Terms:
Molecular Function:
catalytic activity (GO:0003824)
Date:
2024-08-14

Family Accession:
NF014826.5
Method:
HMM

6.

OB-fold nucleic acid binding domain-containing protein

This family contains OB-fold domains that bind to nucleic acids [4]. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (See Pfam:PF00152). Aminoacyl-tRNA synthetases catalyse the addition of an amino acid to the appropriate tRNA molecule EC:6.1.1.-. This family also includes part of RecG helicase involved in DNA repair. Replication factor A is a hetero-trimeric complex, that contains a subunit in this family [2,3]. This domain is also found at the C-terminus of bacterial DNA polymerase III alpha chain. [1]. 2047877. Class II aminoacyl transfer RNA synthetases: crystal structure. of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp).. Ruff M, Krishnaswamy S, Boeglin M, Poterszman A, Mitschler A,. Podjarny A, Rees B, Thierry JC, Moras D;. Science 1991;252:1682-1689.. [2]. 7760808. Rpa4, a homolog of the 34-kilodalton subunit of the replication. protein A complex.. Keshav KF, Chen C, Dutta A;. Mol Cell Biol 1995;15:3119-3128.. [3]. 8990123. Structure of the single-stranded-DNA-binding domain of. replication protein A bound to DNA.. Bochkarev A, Pfuetzner RA, Edwards AM, Frappier L;. Nature 1997;385:176-181.. [4]. 10829230. Protein fold recognition using sequence profiles and its. application in structural genomics.. Koonin EV, Wolf YI, Aravind L;. Adv Protein Chem 2000;54:245-275. (from Pfam)

GO Terms:
Molecular Function:
nucleic acid binding (GO:0003676)
Date:
2024-08-14

Family Accession:
NF013499.5
Method:
HMM

7.
new record, indexing in progress
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9.
new record, indexing in progress
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new record, indexing in progress
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new record, indexing in progress
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12.
new record, indexing in progress
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new record, indexing in progress
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14.
new record, indexing in progress
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15.
new record, indexing in progress
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16.
new record, indexing in progress
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17.
new record, indexing in progress
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18.

DNA polymerase III subunit alpha

DNA polymerase III alpha subunit is one of the three subunits that make up the catalytic core that contains the polymerase active site

Date:
2023-02-23

Family Accession:
11481465
Method:
Sparcle

19.

DNA polymerase III subunit alpha

Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase

Gene:
dnaE
GO Terms:
Molecular Function:
nucleic acid binding (GO:0003676)
Biological Process:
DNA replication (GO:0006260)
Molecular Function:
3'-5' exonuclease activity (GO:0008408)
Date:
2021-07-21

Family Accession:
NF004226.0
Method:
HMM

20.

DNA polymerase III subunit alpha

All proteins in this family for which functions are known are DNA polymerases. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Gene:
dnaE
GO Terms:
Molecular Function:
DNA-directed DNA polymerase activity (GO:0003887)
Biological Process:
DNA replication (GO:0006260)
Molecular Function:
3'-5' exonuclease activity (GO:0008408)
Cellular Component:
DNA polymerase III complex (GO:0009360)
Date:
2024-06-04

Family Accession:
TIGR00594.1
Method:
HMM

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