Protein Family Models

This entry represents the single Cache domain 2 (sCache_2), which contains the long N-terminal helix domain [1]. This domain recognises pyruvate, acetate, propionate, glycolate, L-lactate, acetoacetate, urea and hydroxyurea, acetamide, formamide, L-malate and citromalate, malonate, methyl and bromosuccinate and citraconic acid (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043). [1]. 27049771. Cache Domains That are Homologous to, but Different from PAS. Domains Comprise the Largest Superfamily of Extracellular. Sensors in Prokaryotes.. Upadhyay AA, Fleetwood AD, Adebali O, Finn RD, Zhulin IB;. PLoS Comput Biol. 2016;12:e1004862. (from Pfam)

Date:

2024-08-14

Double Cache domain 2 (dCache_2) may be a result of single Cache domain 2 (sCache_2) duplication [2]. [1]. 11084361. Cache - a signaling domain common to animal Ca(2+)-channel. subunits and a class of prokaryotic chemotaxis receptors.. Anantharaman V, Aravind L;. Trends Biochem Sci 2000;25:535-537.. [2]. 27049771. Cache Domains That are Homologous to, but Different from PAS. Domains Comprise the Largest Superfamily of Extracellular. Sensors in Prokaryotes.. Upadhyay AA, Fleetwood AD, Adebali O, Finn RD, Zhulin IB;. PLoS Comput Biol. 2016;12:e1004862. (from Pfam)

Date:

2024-08-14

COG4564 family protein

Date:

2017-03-02