Protein Family Models for Protein (Select 1834871092) - Protein Family Models

Warning: The NCBI web site requires JavaScript to function. more...

Links from Protein

Items: 6

Select item 4297141.

Transcriptional repressor NrdR-like, N-terminal domain

Date:: 2024-08-14

Family Accession:: NF046381.1
Method:: HMM

Select item 4140412.

ATP cone domain-containing protein

Date:: 2024-08-14

Family Accession:: NF015442.5
Method:: HMM

Select item 3932993.

new record, indexing in progress

Family Accession:

Select item 3507294.

new record, indexing in progress

Family Accession:

Select item 2206785.

transcriptional regulator NrdR

transcriptional regulator NrdR represses transcription of the class Ib ribonucleotide reductase (RNR) genes nrdHIEF, but has a much smaller effect on the transcription of class Ia RNR genes nrdAB and class III RNR genes nrdDG

Date:: 2023-03-13

Family Accession:: 11442498
Method:: Sparcle

Select item 187366.

transcriptional regulator NrdR

Members of this almost entirely bacterial family contain an ATP cone domain (PFAM:PF03477). There is never more than one member per genome. Common gene symbols given include nrdR, ybaD, ribX and ytcG. The member from Streptomyces coelicolor is found upstream in the operon of the class II oxygen-independent ribonucleotide reductase gene nrdJ and was shown to repress nrdJ expression. Many members of this family are found near genes for riboflavin biosynthesis in Gram-negative bacteria, suggesting a role in that pathway. However, a phylogenetic profiling study associates members of this family with the presence of a palindromic signal with consensus acaCwAtATaTwGtgt, termed the NrdR-box, an upstream element for most operons for ribonucleotide reductase of all three classes in bacterial genomes.