Protein Family Models

The N-terminal domain of cytochrome C oxidase contains two transmembrane alpha-helices. [1]. 8638158. The whole structure of the 13-subunit oxidized cytochrome c. oxidase at 2.8 A.. Tsukihara T, Aoyama H, Yamashita E, Tomizaki T, Yamaguchi H,. Shinzawa-Itoh K, Nakashima R, Yaono R, Yoshikawa S;. Science 1996;272:1136-1144. (from Pfam)

Date:

2024-08-14

This enzyme catalyzes the oxidation of quinol with the concomitant reduction of molecular oxygen to water. This acts as the terminal electron acceptor in the respiratory chain. This subunit contains two transmembrane helices and a large external domain responsible for the binding and oxidation of quinol. QuoX is (presently) only found in gram positive bacteria of the Bacillus/Staphylococcus group. Like CyoA, the ubiquinol oxidase found in proteobacteria, the residues responsible for the ligation of Cu(a) and cytochrome c (found in the related cyt. c oxidases) are absent. Unlike CyoA, QoxA is in complex with a subunit I which contains cytochromes a similar to the cyt. c oxidases (as opposed to cytochromes b).

Gene:

qoxA

Date:

2024-06-11

protein similar to quinol oxidase subunit

Date:

2017-03-02